Article
A new essential hypertension susceptibility locus on chromosome 2p24-p25, detected by genomewide search.
American journal of human genetics - 1 Oct 2002
Angius Andrea, Petretto Enrico, Maestrale Giovanni Battista, Forabosco Paola, Casu Giuseppina, Piras Daniela, Fanciulli Manuela, Falchi Mario, Melis Paola Maria, Palermo Mario, Pirastu Mario
Abstract excerpt
Essential hypertension (EH) is a complex disorder that results from the interaction of a number of susceptibility genes and environmental factors. We studied an isolated Sardinian village (Talana) in which the prevalence of hypertension is comparable to that in most Western populations. Talana exhibits features, such as slow demographic growth, high inbreeding, a low number of founders, stable lifestyle and...
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