Article
Virulent Mycobacterium fortuitum restricts NO production by a gamma interferon-activated J774 cell line and phagosome-lysosome fusion.
Infection and immunity - 1 Oct 2002
Da Silva Tânia Regina Marques, De Freitas Juliana Ribeiro, Silva Queilan Chagas, Figueira Cláudio Pereira, Roxo Eliana, Leão Sylvia Cardoso, De Freitas Luiz Antônio Rodrigues, Veras Patrícia Sampaio Tavares
Abstract excerpt
The virulence of different isolates of Mycobacterium has been associated with two morphologically distinguishable colonial variants: opaque (SmOp) and transparent (SmTr). In this report we used an in vitro assay to compare macrophage (Mphi) responses to SmOp and SmTr Mycobacterium fortuitum variants, taking advantage of the fact that these variants were derived from the same isolate. Cells preactivated or not...
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