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Article

Salmonella spp. are cytotoxic for cultured macrophages.

Molecular microbiology - 1 Sept 1996

Chen L M, Kaniga K, Galán J E

Abstract excerpt

We have shown by a variety of microscopical and biochemical techniques that Salmonella spp. are cytotoxic for cultured J774A.1 and bone marrow-derived murine macrophages. The cytotoxicity is initially manifested by inhibition of membrane ruffling and macropinocytosis in infected macrophages, and is followed by cell death. Macrophages killed by Salmonella spp. exhibited features of apoptosis such as condensation...

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PMID: 8885278
DOI: 10.1046/j.1365-2958.1996.471410.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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