Suppressive activity of splenic macrophages induced by transparent and opaque colonial variants of Mycobacterium avium complex against lymphoproliferative response.

doi:10.1111/j.1348-0421.1993.tb03239.x

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Article

Suppressive activity of splenic macrophages induced by transparent and opaque colonial variants of Mycobacterium avium complex against lymphoproliferative response.

Microbiology and immunology - 1 Jan 1993

Tomioka H, Saito H

Abstract excerpt

Splenic macrophages (M phi s) induced by the two colonial variants of Mycobacterium avium complex, SmT variant (smooth, transparent, flat) and SmD variant (smooth, opaque, domeshaped), were studied for their suppressive activity against mitogenic response of splenic T cells to concanavalin A (ConA). The SmT variant is much more virulent than the SmD variant and causes more severe infection in host mice. Moreover,...

Topics

Animals
Female
Immune Tolerance
Luminescent Measurements
Lymphocyte Activation
Macrophage Activation
Macrophages
Male
Mice
Mice, Inbred BALB C
Mice, Inbred CBA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitogens

Mycobacterium avium

Phenotype

Spleen

T-Lymphocytes

Tuberculosis

Source

Open in PubMed

Identifiers

PMID: 8231963
DOI: 10.1111/j.1348-0421.1993.tb03239.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8231963-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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