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Article

Isolation of vaccine-derived type 1 polioviruses displaying similar properties to virulent wild strain Mahoney from sewage in Japan.

Journal of medical virology - 1 Nov 2002

Horie Hitoshi, Yoshida Hiromu, Matsuura Kumiko, Miyazawa Miwako, Wakabayashi Kengo, Nomoto Akio, Hashizume So

Abstract excerpt

Type 1, 2, and 3 vaccine-derived polioviruses were isolated from a sewage disposal plant located downstream of the Oyabe River in Toyama Prefecture, Japan, between October 1993 and September 1995. Neurovirulence was analyzed in 13 type 1 vaccine-derived strains, using mutant analysis by polymerase chain reaction and restriction enzyme cleavage (MAPREC). Nine strains (69%) were estimated to have marked...

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PMID: 12226835
DOI: 10.1002/jmv.10224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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