Isolation of vaccine-derived type 1 polioviruses displaying similar properties to virulent wild strain Mahoney from sewage in Japan.

doi:10.1002/jmv.10224

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Article

Isolation of vaccine-derived type 1 polioviruses displaying similar properties to virulent wild strain Mahoney from sewage in Japan.

Journal of medical virology - 1 Nov 2002

Horie Hitoshi, Yoshida Hiromu, Matsuura Kumiko, Miyazawa Miwako, Wakabayashi Kengo, Nomoto Akio, Hashizume So

Abstract excerpt

Type 1, 2, and 3 vaccine-derived polioviruses were isolated from a sewage disposal plant located downstream of the Oyabe River in Toyama Prefecture, Japan, between October 1993 and September 1995. Neurovirulence was analyzed in 13 type 1 vaccine-derived strains, using mutant analysis by polymeras...

Topics

Animals
Antibodies, Monoclonal
Antibodies, Viral
Humans
Japan
Mutation
Neutralization Tests
Poliovirus
Poliovirus Vaccine, Oral
Polymerase Chain Reaction
Restriction Mapping
Sewage
Temperature
Viral Plaque Assay
Virulence
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 12226835
DOI: 10.1002/jmv.10224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-12226835-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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