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Article

Genetic variation of hepatitis B surface antigen coding region among infants with chronic hepatitis B virus infection.

Journal of medical virology - 1 Nov 2002

Nainan Omana V, Khristova Marina L, Byun KwanSoo, Xia Guoliang, Taylor Patricia E, Stevens Cladd E, Margolis Harold S

Abstract excerpt

Variants in the amino acid composition of the primary antibody-binding site of hepatitis B surface antigen (HBsAg) have been identified in a number of populations with chronic hepatitis B virus (HBV) infection. Direct sequencing of amplified or cloned PCR products, solid phase detection of sequence-specific PCR products (SP-PCR), and limiting dilution cloning PCR (LDC-PCR) were compared to determine their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12226817
DOI: 10.1002/jmv.10206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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