Article
Molecular epidemiology of hepatitis B virus vaccine variants in Singapore.
Vaccine - 1 Jan 1995
Oon C J, Lim G K, Ye Z, Goh K T, Tan K L, Yo S L, Hopes E, Harrison T J, Zuckerman A J
Abstract excerpt
Perinatal infection with variants of hepatitis B virus occurs despite combined immunoprophylaxis with hepatitis B immunoglobulin and currently licensed plasma-derived and recombinant yeast hepatitis B vaccines. Several variants have been detected during a large study of infants born to carrier mothers in Singapore. The most frequent variant was a virus in which a single amino acid substitution Gly to Arg occurred...
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