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Article

Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy.

American journal of physiology. Cell physiology - 1 Oct 2002

Chargé Sophie B P, Brack Andrew S, Hughes Simon M

Abstract excerpt

To investigate the cause of skeletal muscle weakening during aging we examined the sequence of cellular changes in murine muscles. Satellite cells isolated from single muscle fibers terminally differentiate progressively less well with increasing age of donor. This change is detected before decline in satellite cell numbers and all histological changes examined here. In MSVski transgenic mice, which show type IIb...

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Source

Identifiers

PMID: 12225986
DOI: 10.1152/ajpcell.00206.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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