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Article

The altered fate of aging satellite cells is determined by signaling and epigenetic changes

20 Feb 2015

Abstract excerpt

Skeletal muscle is a striated tissue composed of multinucleated fibers that contract under the control of the somatic nervous system to direct movement. The stem cells of skeletal muscle, known as satellite cells, are responsible for muscle fiber growth, turnover, and regeneration. Satellite cells are activated and proliferate in response to stimuli, and simplistically, have two main fates-to repopulate the...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 25750654
DOI: 10.3389/fgene.2015.00059

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