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Article

Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress.

American journal of physiology. Cell physiology - 1 Oct 2002

Grange Robert W, Gainer Thomas G, Marschner Krista M, Talmadge Robert J, Stull James T

Abstract excerpt

Loss of the dystrophin-glycoprotein complex from muscle sarcolemma in Duchenne's muscular dystrophy (DMD) renders the membrane susceptible to mechanical injury, leaky to Ca(2+), and disrupts signaling, but the precise mechanism(s) leading to the onset of DMD remain unclear. To assess the role of mechanical injury in the onset of DMD, extensor digitorum longus (EDL) muscles from C57 (control), mdx, and...

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Source

Identifiers

PMID: 12225973
DOI: 10.1152/ajpcell.00450.2001

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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