Article
The TRTGn motif stabilizes the transcription initiation open complex.
Journal of molecular biology - 20 Sept 2002
Voskuil Martin I, Chambliss Glenn H
Abstract excerpt
The effect on transcription initiation by the extended -10 motif (5'-TRTG(n)-3'), positioned upstream of the -10 region, was investigated using a series of base substitution mutations in the alpha-amylase promoter (amyP). The extended -10 motif, previously referred to as the -16 region, is found frequently in Gram-positive bacterial promoters and several extended -10 promoters from Escherichia coli. The...
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