Frequency of tau mutations in familial and sporadic frontotemporal dementia and other tauopathies.

doi:10.1007/s00415-004-0489-x

Article

Frequency of tau mutations in familial and sporadic frontotemporal dementia and other tauopathies.

Journal of neurology - 1 Sept 2004

Stanford Prudence M, Brooks William S, Teber Erdahl T, Hallupp Marianne, McLean Catriona, Halliday Glenda M, Martins Ralph N, Kwok John B J, Schofield Peter R

Abstract excerpt

Tau gene mutations with insoluble Tau neuropathology have been identified in pedigrees with frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). Other neurodegenerative diseases, including progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), are also characterised by insoluble Tau neuropathology. This study sought to determine the nature and frequency of tau gene...

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Frequency of tau mutations in familial and sporadic frontotemporal dementia and other tauopathies.

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