Article
Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.
Human molecular genetics - 15 Sept 2002
Wang P Jeremy, Page David C
Abstract excerpt
TAF(II)250, the largest subunit of the general transcription factor TFIID, is expressed from the human X chromosome, at least in somatic cells. In male meiosis, however, the sex chromosomes are transcriptionally silenced, while the autosomes remain active. How then are protein-encoding genes transcribed during human male meiosis? Here we present a novel autosomal human gene, TAF1L, which is homologous to...
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