Article
Functional polymorphism in H2BFWT‐5′UTR is associated with susceptibility to male infertility
6 Jul 2009
Abstract excerpt
H2B histone family, member W, testis-specific (H2BFWT) gene encodes a testis-specific histone that becomes incorporated into sperm chromatin. A male infertility-associated single nucleotide polymorphism (-9C > T) within the 5' untranslated region (5'UTR) of the H2BFWT gene was identified by direct sequencing. Statistical association studies showed the polymorphism significantly associated with male infertility (n...
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