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Article

Fidgetin-like1 is a strong candidate for a dynamic impairment of male meiosis leading to reduced testis weight in mice.

PloS one - 1 Jan 2011

L'Hôte David, Vatin Magalie, Auer Jana, Castille Johan, Passet Bruno, Montagutelli Xavier, Serres Catherine, Vaiman Daniel

Abstract excerpt

BACKGROUND: In a previous work, using an interspecific recombinant congenic mouse model, we reported a genomic region of 23 Mb on mouse chromosome 11 implicated in testis weight decrease and moderate teratozoospermia (∼20-30%), a Quantitative Trait Locus (QTL) called Ltw1. The objective of the present study is to identify the gene underlying this phenotype. RESULTS: In the present study, we refined the QTL...

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Identifiers

PMID: 22110678
DOI: 10.1371/journal.pone.0027582
PMCID: PMC3217987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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