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Platelet transfusions in haploidentical haematopoietic stem cell allograft candidates: Protecting HLA-A and HLA-B antigens through eplet analysis.

HLA - 1 Mar 2024

Durand Gatien, Desoutter Judith, Lorriaux Corinne, Poumaredes Géraldine, Joris Magalie, Charbonnier Amandine, Lebon Delphine, Paubelle Etienne, Garcon Loïc, Guillaume Nicolas

Abstract excerpt

In patients awaiting an allogeneic haematopoietic stem cell transplantation, platelet transfusion is a risk factor for anti-HLA class I immunization because the resulting donor-specific antibodies complicate the allograft process. The objective of the present study was to determine the feasibility of a novel eplet-based strategy for identifying HLA class I mismatches between potential donors and the recipient...

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PMID: 38516935
DOI: 10.1111/tan.15438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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