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Article

How to select the best available related or unrelated donor of hematopoietic stem cells?

31 May 2016

Abstract excerpt

Recognition of HLA incompatibilities by the immune system represents a major barrier to allogeneic hematopoietic stem cell transplantation. HLA genotypically identical sibling donors are, therefore, the gold standard for transplantation purposes, but only 30% patients have such a donor. For the remaining 70% patients alternative sources of stem cells are a matched unrelated adult volunteer donor, a haploidentical...

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PMID: 27252513
DOI: 10.3324/haematol.2015.141119

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