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Article

Donor selection for allogeneic hematopoietic cell transplantation

3 Apr 2023

Abstract excerpt

BACKGROUND: In Germany, each year over 3000 patients with malignant and non-malignant hematologic and systemic diseases are treated by allo - geneic hematopoietic cell transplantation (HCT). Genetic donor-recipient disparities, especially those concerning variable human leukocyte antigens (HLA), mediate both an immunotherapeutic effect and the risk of damage to healthy tissues ("graft-versus-host disease"). The...

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PMID: 36949660
DOI: 10.3238/arztebl.m2023.0031

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