Molecular techniques for typing unrelated marrow donors: potential impact of molecular typing disparity on donor selection.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Molecular techniques for typing unrelated marrow donors: potential impact of molecular typing disparity on donor selection.

Bone marrow transplantation - 1 Jan 1994

Baxter-Lowe L A

Abstract excerpt

HLA matching between a bone marrow recipient and donor is one of the major factors influencing transplant success. However, it is not possible to locate an HLA-identical donor for about 70% of patients who might benefit from bone marrow transplantation (BMT). New molecular biological methods for detection of HLA polymorphism currently provide an opportunity to improve HLA matching of unrelated donors as well as a...

Topics

Adult
Alleles
Amino Acid Sequence
Bone Marrow Transplantation
Cohort Studies
Graft Rejection
Graft vs Host Disease
HLA Antigens
Histocompatibility
Histocompatibility Testing
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Sequence Alignment

Sequence Homology, Amino Acid

Serology

Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 7728125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7728125-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular techniques for typing unrelated marrow donors: potential impact of molecular typing disparity on donor selection.PMID 7728125Read ↗

HLA matching in allogeneic stem cell transplantationSemantic proximity Read ↗

HLA Matching in Unrelated Stem Cell Transplantation up to DateSemantic proximity Read ↗

How to select the best available related or unrelated donor of hematopoietic stem cells?Semantic proximity Read ↗

The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantationSemantic proximity Read ↗

Association of HLA-C Disparity With Graft Failure After Marrow Transplantation From Unrelated DonorsSemantic proximity Read ↗

Molecular basis of HLA polymorphism: implications in clinical transplantationSemantic proximity Read ↗

HLA matching in hematopoietic cell transplantation.Semantic proximity Read ↗

The impact of HLA genotyping on survival following unrelated donor haematopoietic stem cell transplantationSemantic proximity Read ↗

Impact of HLA matching on hematopoietic cell transplants from unrelated donors.Semantic proximity Read ↗

Frequent HLA class I and DP sequence mismatches in serologically (HLA-A, HLA-B, HLA-DR) and molecularly (HLA-DRB1, HLA-DQA1, HLA-DQB1) HLA-identical unrelated bone marrow transplant pairs.Semantic proximity Read ↗

Automated nucleotide sequencing reveals substantial disparity between the HLA-A2 genes of bone marrow transplant recipients and donors.Semantic proximity Read ↗

Tissue typing in support of unrelated hematopoietic cell transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.