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Article

The <i>SSX</i> gene family: Characterization of 9 complete genes

3 Sept 2002

Abstract excerpt

Human SSX genes comprise a gene family with 6 known members. SSX1, 2 and 4 have been found to be involved in the t(X;18) translocation characteristically found in all synovial sarcomas. Four (SSX1, 2, 4 and 5) are known to be expressed in a subset of tumors and testis, and anti-SSX antibodies have been found in sera from cancer patients. SSX antigens are thus typical cancer-testis (CT) antigens. To identify...

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PMID: 12216073
DOI: 10.1002/ijc.10634

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