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Article

A novel fusion gene, <i>SS18L1/SSX1</i>, in synovial sarcoma

1 Apr 2003

Abstract excerpt

Synovial sarcoma is an aggressive soft tissue tumor that is characterized cytogenetically by the t(X;18)(p11;q11) translocation, resulting in fusion between the SS18 gene on chromosome 18 and one of the SSX genes on the X chromosome. The three fusion genes that have been detected thus far, SS18/SSX1, SS18/SSX2, and SS18/SSX4, account for more than 95% of the synovial sarcomas. Because SS18/SSX fusions do not seem...

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PMID: 12696068
DOI: 10.1002/gcc.10210

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