Article
Interleukin genetic variants and the risk of renal failure in infants with infection.
Pediatric nephrology (Berlin, Germany) - 1 Sept 2002
Treszl András, Tóth-Heyn Péter, Kocsis István, Nobilis András, Schuler Agnes, Tulassay Tivadar, Vásárhelyi Barna
Abstract excerpt
Systemic infection is a major risk factor for the development of neonatal acute renal failure (ARF). We investigated whether genetic polymorphisms of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, and IL-10 genes leading to a more intense inflammatory response might predispose very low birth weight (VLBW) infants to the development of ARF in severe infection. The medical records of 92 VLBW...
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