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Article

Impact of cytokine genetic polymorphisms on the risk of renal parenchymal infection in children.

Journal of pediatric urology - 1 Dec 2017

Hussein Almontaser, Askar Eman, Badawy Ahlam, Saad Khaled, Zahran Asmaa, Elderwy Ahmad A

Abstract excerpt

BACKGROUND: Acute pyelonephritis is associated with renal scarring in up to 30% of patients. Renal scarring may cause significant long-term morbidity. The pathogenesis of acute pyelonephritis remains unclear, although it involves interaction among uroepithelium, the immune system cells, and the locally produced cytokines. That some UTI-prone children develop acute pyelonephritis, and eventually renal parenchymal...

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Source

Identifiers

PMID: 28716390
DOI: 10.1016/j.jpurol.2017.05.025

Genes

CXCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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