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Article

Superantigenicity of streptococcal M protein.

1 Jul 1990

Abstract excerpt

M proteins that define the serotypes of group A streptococci are powerful blastogens for human T lymphocytes. The mechanism by which they activate T cells was investigated and compared with the conventional T cell mitogen phytohemagglutinin, and the known superantigen staphylococcal enterotoxin B. Although major histocompatibility complex (MHC) class II molecules are required for presentation, there is no MHC...

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Identifiers

PMID: 2358781
DOI: 10.1084/jem.172.1.359

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