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Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application

16 Jan 2025

Abstract excerpt

Reprogramming energy metabolism is pivotal to tumor development. Ketone bodies (KBs), which are generated during lipid metabolism, are fundamental bioactive molecules that can be modulated to satisfy the escalating metabolic needs of cancer cells. At present, a burgeoning body of research is concentrating on the metabolism of KBs within tumors, investigating their roles as signaling mediators, drivers of...

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PMID: 39857793
DOI: 10.3390/biomedicines13010210

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