Article
Peroxisome deficiency represses the expression of n-alkane-inducible YlALK1 encoding cytochrome P450ALK1 in Yarrowia lipolytica.
FEMS microbiology letters - 27 Aug 2002
Sumita Toru, Iida Toshiya, Hirata Aiko, Horiuchi Hiroyuki, Takagi Masamichi, Ohta Akinori
Abstract excerpt
Among the eight genes (YlALK1-YlALK8) encoding P450 cytochromes of the CYP52 family of the n-alkane-assimilating yeast Yarrowia lipolytica, Y1ALK1 is most highly induced by n-alkanes with short hydrocarbon chains, such as n-decane, and involved in the initial hydroxylation of n-alkane. To determine the factors regulating YlALK1 expression, we isolated an n-decane assimilation-deficient mutant, B0-6-1, whose...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.