Article
Disrupting a phospholipase A2 gene increasing lipid accumulation in the oleaginous yeast Yarrowia lipolytica.
Journal of applied microbiology - 1 Jan 2021
Li J X, Xu J, Ruan J C, Meng H M, Su H, Han X F, Lu M, Li F L, Wang S A
Abstract excerpt
AIMS: Phospholipase A2 (PLA2 ) is a diverse superfamily that hydrolyzes fatty acyl ester bonds at the sn-2 position of phospholipids. The correlation between phospholipid metabolism and the anabolism of neutral lipids remains unclear in yeasts. This study aims to explore the effects of PLA2 on lipid accumulation in the oleaginous yeast Yarrowia lipolytica. METHODS AND RESULTS: This study identified an actively...
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