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Article

Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2002

Hong C-J, Wang Y-C, Tsai S-J

Abstract excerpt

Angiotensin-converting enzyme (ACE) inhibitor has mood-elevating effects, and central ACE activity is increased for suicidal patients. In addition, substance P (SP), which is degraded by ACE, has been implicated in the pathogenesis of, and evaluated in the treatment for, major depressive disorder (MDD). The present study has tested the hypothesis that an ACE-gene insertion/deletion (I/D) polymorphism is...

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Share to Antidepressive Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12203048
DOI: 10.1007/s00702-001-0686-z

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders.PMID 12203048Read ↗

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No association of an insertion/deletion polymorphism in the angiotensin I converting enzyme gene with bipolar or unipolar affective disorders.Semantic proximity Read ↗

Angiotensin I-converting enzyme I/D polymorphism and suicidal behaviors.Semantic proximity Read ↗

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