Article
Genetic variants in the angiotensin I-converting-enzyme (ACE) and angiotensin II receptor (AT1) gene and clinical outcome in depression.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2005
Bondy Brigitta, Baghai Thomas C, Zill Peter, Schule Cornelius, Eser Daniela, Deiml Tobias, Zwanzger Peter, Ella Robin, Rupprecht Rainer
Abstract excerpt
The insertion/(I)/deletion (D) polymorphism of the angiotensin-converting enzyme gene (ACE) is of increasing interest in etiology and treatment of various neuropsychiatric disorders. The present study aimed to replicate own earlier findings that depressive patients with the ACE D-allele are responding better to treatment with antidepressants than those with the II genotype. We further investigated a common...
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