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Article

Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders.

The international journal of neuropsychopharmacology - 1 Dec 2005

Mendlewicz Julien, Oswald Pierre, Claes Stephan, Massat Isabelle, Souery Daniel, Van Broeckhoven Christine, Del-Favero Jurgen

Abstract excerpt

In the search of genes potentially implicated in the aetiology of affective disorders (AD), SUBSTANCE P (SP) pathway is receiving increased interest. SP receptor antagonists, such as MK-869 and L-759274, have been shown to have antidepressant effect. Results from preclinical and human studies implicate SP and its pathway in the pathophysiology of mood disorders. We investigated a possible association between 20...

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PMID: 15927090
DOI: 10.1017/S1461145705005444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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