Article
Association between Insertion-Deletion Polymorphism of the Angiotensin-Converting Enzyme Gene and Treatment Response to Antipsychotic Medications: A Study of Antipsychotic-Naïve First-Episode Psychosis Patients and Nonadherent Chronic Psychosis Patients.
International journal of molecular sciences - 12 Oct 2022
Nadalin Sergej, Dević Pavlić Sanja, Peitl Vjekoslav, Karlović Dalibor, Zatković Lena, Ristić Smiljana, Buretić-Tomljanović Alena, Jakovac Hrvoje
Abstract excerpt
We investigated whether a functional insertion/deletion (I/D) polymorphism of angiotensin-converting enzyme (ACE) influenced antipsychotic treatment. At baseline, and after 8 weeks of treatment with various antipsychotic medications, we assessed patients’ Positive and Negative Syndrome Scale (PANSS) scores, PANSS factors, and metabolic-syndrome-related parameters (fasting plasma lipid and glucose levels, and body...
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