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Article

Association of ACE Gene Insertion/Deletion Polymorphism with Suicidal Attempt in an Iranian Population.

Biochemical genetics - 1 Feb 2021

Ghorbani Elham, Mohammadi Mahsa, Malakouti Seyed Kazem, Mohammadi-Kangarani Hamed, Abdollahi Elaheh, Torab Mansour, Rahimi-Moghaddam Parvaneh

Abstract excerpt

Deregulation of the renin-angiotensin system (RAS) plays an important role in suicide. Angiotensin converting enzyme (ACE) gene is a key component in this system. The relationship between insertion/deletion (I/D) polymorphism of ACE gene with suicide attempt (SA) is controversial. According to previous studies, allele D in this polymorphism has been considered as a potential risk factor for suicide. However, no...

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PMID: 32720141
DOI: 10.1007/s10528-020-09986-7

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