Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis C virus genotyping: interrogation of the 5' untranslated region cannot accurately distinguish genotypes 1a and 1b.

Journal of clinical microbiology - 1 Sept 2002

Chen Zhenyu, Weck Karen E

Abstract excerpt

Although the 5' untranslated region (5' UTR) is the most conserved region of the hepatitis C virus (HCV) genome, it has been suggested that interrogation of this region is sufficient for determination of the HCV genotype. We compared two methods of determination of the HCV genotype: (i) direct sequencing of the DNA of the NS-5b region and (ii) reverse line probe assay (LiPA; INNO-LiPA HCV II; Innogenetics N.V.)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Diagnostic Errors
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C

Share to Nucleic Acid Hybridization

Share to Reagent Kits, Diagnostic

Share to Viral Nonstructural Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12202542
DOI: 10.1128/JCM.40.9.3127-3134.2002
PMCID: PMC130800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis C virus genotyping: interrogation of the 5' untranslated region cannot accurately distinguish genotypes 1a and 1b.PMID 12202542Read ↗

Evaluation of sequencing of HCV core/E1, NS5A and NS5B as a genotype predictive tool in comparison with commercial assays targeting 5'UTR.Semantic proximity Read ↗

Comparison of three different HCV genotyping methods: core, NS5B sequence analysis and line probe assay.Semantic proximity Read ↗

Comparison of hepatitis C virus subtyping by ns5b sequencing with 5'utr based methods.Semantic proximity Read ↗

Sequencing assays for failed genotyping with the versant hepatitis C virus genotype assay (LiPA), version 2.0.Semantic proximity Read ↗

Hepatitis C virus (HCV) genotype 1 subtype identification in new HCV drug development and future clinical practice.Semantic proximity Read ↗

NS3 genomic sequencing and phylogenetic analysis as alternative to a commercially available assay to reliably determine hepatitis C virus subtypes 1a and 1b.Semantic proximity Read ↗

Rapid genotyping of hepatitis C virus RNA-isolates obtained from patients residing in western Europe.Semantic proximity Read ↗

Evaluation of a new-generation line-probe assay that detects 5' untranslated and core regions to genotype and subtype hepatitis C virus.Semantic proximity Read ↗

Genotyping hepatitis C viruses from Southeast Asia by a novel line probe assay that simultaneously detects core and 5' untranslated regions.Semantic proximity Read ↗

Sequence analysis of hepatitis C virus genotypes 1 to 5 reveals multiple novel subtypes in the Benelux countries.Semantic proximity Read ↗

Important factors in reliable determination of hepatitis C virus genotype by use of the 5' untranslated region.Semantic proximity Read ↗

Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.