Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combining sperm plug genotyping and coat color chimerism predicts germline transmission.

Transgenic research - 1 Dec 2013

Lee Angus Yiu-Fai, Evans Kristin, Willis Brandon, Lloyd K C Kent

Abstract excerpt

There has been a significant increase in the use of C57BL/6N-derived ES cells for the production of gene knockout mice. However, the potential for germline transmission (GLT) from chimeras on this genetic background has been observed to be highly variable. Using coat color as an indicator of somatic chimerism to infer the extent of chimeric contribution to the germ cell population, even highly agouti...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chimera
Share to Embryo, Mammalian
Share to Embryonic Stem Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotyping Techniques

Share to Germ Cells

Share to Mice, Knockout

Share to Pigments, Biological

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 23860911
DOI: 10.1007/s11248-013-9731-6
PMCID: PMC3838463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combining sperm plug genotyping and coat color chimerism predicts germline transmission.PMID 23860911Read ↗

Rescue of germline transmission from chimeras by IVF after sperm analysis.Semantic proximity Read ↗

Identification of germline competent chimaeras by copulatory plug genotyping.Semantic proximity Read ↗

A new coat color mouse line for testing germline transmission of embryonic stem cells while retaining an inbred genetic background.Semantic proximity Read ↗

Genotype, phenotype, and karyotype correlation in the XO mouse model of Turner Syndrome.Semantic proximity Read ↗

Quantitative estimation of chimerism in mice using microsatellite markers.Semantic proximity Read ↗

Genetic and phenotypic influences on copulatory plug survival in mice.Semantic proximity Read ↗

Effects of Genetic Captive-Breeding Protocols on Sperm Quality and Fertility in the White-Footed Mouse1Semantic proximity Read ↗

Utility of a C57BL/6 ES line versus 129 ES lines for targeted mutations in mice.Semantic proximity Read ↗

An extreme bias in the germ line of XY C57BL/6<->XY FVB/N chimaeric mice.Semantic proximity Read ↗

Phenotype and fertilizing capacity of spermatozoa of chimaeric mice produced from two strains that differ in sperm quality.Semantic proximity Read ↗

DNA analysis from stool samples: a fast and reliable method avoiding invasive sampling methods in mouse models of bleeding disorders.Semantic proximity Read ↗

Meiotic drive changes sperm precedence patterns in house mice: potential for male alternative mating tactics?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.