Transmission distortion of t-haplotypes is due to interactions between meiotic partners.

doi:10.1038/313143a0

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Article

Transmission distortion of t-haplotypes is due to interactions between meiotic partners.

Nature - 1 Jan 2000

Seitz A W, Bennett D

Abstract excerpt

The T/t-complex of the mouse includes a series of recessive lethal and semi-lethal mutations but, despite such lethalities, mutant t-haplotypes are found in high frequency in wild mouse populations. This polymorphism is apparently maintained because heterozygous males preferentially transmit the...

Topics

Alleles
Animals
Chimera
Genes, Lethal
Male
Meiosis
Mice
Polymorphism, Genetic
Spermatogenesis

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