Article
Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis.
Gastroenterology - 1 Sept 2002
Marshall Aiden C j, Alderuccio Frank, Toh Ban-Hock
Abstract excerpt
BACKGROUND & AIMS: Experimental autoimmune gastritis (EAG), characterized by a gastric mononuclear cell infiltrate, mucosal cell damage, and autoantibodies to parietal cell-associated H(+)/K(+) adenosine triphosphatase, is a model for human autoimmune gastritis that leads to pernicious anemia. Previous in vitro studies have implicated Fas/CD95 in initiating damage to gastric mucosal cells in humans and an animal...
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