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Article

Cognitive change and the APOE epsilon 4 allele.

Nature - 29 Aug 2002

Deary Ian J, Whiteman Martha C, Pattie Alison, Starr John M, Hayward Caroline, Wright Alan F, Carothers Andrew, Whalley Lawrence J

Abstract excerpt

There is a marked variation in whether people retain sufficient cognitive function to maintain their quality of life and independence in old age, even among those without dementia, so it would be valuable to identify the determinants of normal age-related cognitive change. We have retested non-demented 80-year-olds who were participants in the Scottish Mental Survey of 1932, and find that the variation in their...

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Source

Identifiers

PMID: 12198535
DOI: 10.1038/418932a

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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