Article
Epstein-Barr virus in gastric adenocarcinomas: association with ethnicity and CDKN2A promoter methylation
26 Aug 2002
Abstract excerpt
AIMS: It has been shown previously (by immunohistochemistry) that gastric adenocarcinomas harbouring Epstein-Barr virus (EBV) frequently lose p16 protein. This study aimed to examine the mechanisms of inactivation of the CDKN2A gene and correlate the results with clinicopathological features. METHODS: Methylation specific polymerase chain reaction was used to detect CDKN2A promoter methylation in gastric...
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