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Article

Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatments

1 Jan 2014

Abstract excerpt

Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) comprises nearly 10% of gastric carcinoma cases worldwide. Recently, it was recognised to have unique clinicopathologic characteristics, including male predominance, lower rates of lymph node involvement, and better prognosis. EBVaGC is further characterised by abnormal hypermethylation of tumour suppressor gene promoter regions, causing...

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PMID: 24914366
DOI: 10.3748/wjg.v20.i21.6448

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