Article
Genomic assays for Epstein-Barr virus-positive gastric adenocarcinoma.
Experimental & molecular medicine - 23 Jan 2015
Gulley Margaret L
Abstract excerpt
A small set of gastric adenocarcinomas (9%) harbor Epstein-Barr virus (EBV) DNA within malignant cells, and the virus is not an innocent bystander but rather is intimately linked to pathogenesis and tumor maintenance. Evidence comes from unique genomic features of host DNA, mRNA, microRNA and CpG methylation profiles as revealed by recent comprehensive genomic analysis by The Cancer Genome Atlas Network. Their...
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