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Epstein-Barr virus-specific methylation of human genes in gastric cancer cells

1 Dec 2010

Abstract excerpt

BACKGROUND: Epstein-Barr Virus (EBV) is found in 10% of all gastric adenocarcinomas but its role in tumor development and maintenance remains unclear. The objective of this study was to examine EBV-mediated dysregulation of cellular factors implicated in gastric carcinogenesis. METHODS: Gene expression patterns were examined in EBV-negative and EBV-positive AGS gastric epithelial cells using a low density...

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PMID: 21194482
DOI: 10.1186/1750-9378-5-27

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