Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determination of the factor V Leiden single-nucleotide polymorphism in a commercial clinical laboratory by use of NanoChip microelectronic array technology.

Clinical chemistry - 1 Sept 2002

Evans Jess G, Lee-Tataseo Cindy

Abstract excerpt

BACKGROUND: Methods for analysis of the single-nucleotide polymorphism (SNP) known as factor V Leiden (FVL) are described. The technique provides rapid, highly accurate detection of the point mutation that encodes for replacement of arginine-506 with glutamine. After formal assay qualification, 758 clinical samples that had previously been analyzed by the Invader Monoplex Assay were tested as research samples in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoanalysis
Share to Factor V
Share to Oligonucleotide Array Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 12194915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determination of the factor V Leiden single-nucleotide polymorphism in a commercial clinical laboratory by use of NanoChip microelectronic array technology.PMID 12194915Read ↗

Diagnostic single nucleotide polymorphism analysis of factor V Leiden and prothrombin 20210G > A. A comparison of the Nanogen Eelectronic Microarray with restriction enzyme digestion and the Roche LightCycler.Semantic proximity Read ↗

An improved electronic microarray-based diagnostic assay for identification of MEFV mutations.Semantic proximity Read ↗

Microelectronic array system for molecular diagnostic genotyping: Nanogen NanoChip 400 and molecular biology workstation.Semantic proximity Read ↗

Evolving methods for single nucleotide polymorphism detection: Factor V Leiden mutation detection.Semantic proximity Read ↗

Evaluation of electronic microarrays for genotyping factor V, factor II, and MTHFR.Semantic proximity Read ↗

Analysis of clinically relevant single-nucleotide polymorphisms by use of microelectronic array technology.Semantic proximity Read ↗

Analysis of LDLR mutations in familial hypercholesterolemia patients in Greece by use of the NanoChip microelectronic array technology.Semantic proximity Read ↗

Beta-thalassemia microelectronic chip: a fast and accurate method for mutation detection.Semantic proximity Read ↗

Colorimetric microwell plate detection of the factor V Leiden mutation.Semantic proximity Read ↗

Multicenter evaluation of PCR methods for the detection of factor V Leiden (R506Q) genotypes.Semantic proximity Read ↗

Automated detection of the factor V Leiden mutation using the LCx microparticle enzyme immunoassay.Semantic proximity Read ↗

Allelic drop-out in the LDLR gene affects mutation detection in familial hypercholesterolemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.