Article
Evaluation of electronic microarrays for genotyping factor V, factor II, and MTHFR.
Clinical chemistry - 1 May 2003
Erali Maria, Schmidt Ben, Lyon Elaine, Wittwer Carl
Abstract excerpt
BACKGROUND: Genetic risk factors associated with venous thrombosis include mutations in the factor V (Leiden), factor II (prothrombin), and methylenetetrahydrofolate reductase (MTHFR) genes. We evaluated a method using electronically addressable microarrays for the detection of mutations in these genes that have been associated with vascular disease. METHODS: The NanoChip Molecular Biology Workstation (Nanogen)...
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