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Article

Bcr-Abl variants: biological and clinical aspects.

Leukemia research - 1 Aug 2002

Advani Anjali S, Pendergast Ann Marie

Abstract excerpt

Bcr-Abl is an oncogene that arises from fusion of the Bcr gene with the c-Abl proto-oncogene. Three different Bcr-Abl variants can be formed, depending on the amount of Bcr gene included: p185, p210, and p230. The three variants are associated with distinct types of human leukemias. Examination of the signaling pathways differentially regulated by the Bcr-Abl proteins will help us gain better insight into Bcr-Abl...

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PMID: 12191565
DOI: 10.1016/s0145-2126(01)00197-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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