Article
A review on characterization of BCR - ABL transcript variants for molecular monitoring of chronic myeloid leukemia phenotypes.
Hematology (Amsterdam, Netherlands) - 1 Dec 2023
Zenebe Benyam, Nigussie Helen, Belay Gurja, Seboka Nigussie
Abstract excerpt
Chronic myeloid leukemia (CML) is a clonal myeloproliferative growth of human pluripotent stem cells which is estimated to occur at a rate of 1/100000 populations every year worldwide. A characteristic feature of this disease is the presence of the Philadelphia chromosome genotype, which results from the reciprocal translocation between human chromosomes 9 and 22. Two types of major genotypes are involved, which...
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