Article
p53 mutation in nonmelanoma skin cancers occurring in psoralen ultraviolet a-treated patients: evidence for heterogeneity and field cancerization.
The Journal of investigative dermatology - 1 Aug 2002
Stern Robert S, Bolshakov Svetlana, Nataraj Arun J, Ananthaswamy Honnavara N
Abstract excerpt
A combination of psoralens and ultraviolet A radiation is widely used to treat psoriasis. Long-term, high-dose exposure to psoralen + ultraviolet A is associated with an increased risk of nonmelanoma skin cancer, particularly squamous cell carcinoma. In this study, we used p53 mutations as a mole...
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