Article
p53 gene mutations in Bowen's disease in Koreans: clustering in exon 5 and multiple mutations.
Cancer letters - 29 Sept 2000
Lee H J, Kim J S, Ha S J, Roh K Y, Seo E J, Park W S, Lee J Y, Park K S, Kim J W
Abstract excerpt
We analyzed the p53 protein expression and gene mutations to evaluate the role of ultraviolet radiation or other carcinogens, and possible racial differences in 17 samples from 12 Korean patients with Bowen's disease. A simple microdissection technique was used to collect the tumor cells selectively. p53 protein expression was found in eight of 17 (47%) samples. Abnormalities in polymerase chain reaction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
