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Article

Hereditary Pancreatitis Related to SPINK-1 Mutation. Is There an Increased Risk of Developing Pancreatic Cancer?

Journal of gastrointestinal cancer - 1 Mar 2023

Enjuto Diego T, Herrera Norberto, J Ceinos Carmen, Ramos Bonilla Antonio, Llorente-Lázaro Rosa, González Guerreiro Judit, Castro-Carbajo Pilar

Abstract excerpt

It is thought that many of the idiopathic pancreatitis could have a genetic base. Approximately 50% of them correspond to CFTR (cystic fibrosis transmembrane conductance regulator gene) and SPINK-1 (serine protease inhibitor Kazal type 1) mutations. A recent study compares patients with acute pancreatitis and SPINK-1 mutation with patients with idiopathic acute pancreatitis. The study highlights a 12-fold...

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PMID: 34807350
DOI: 10.1007/s12029-021-00729-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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