Article
Genetic requirements for homologous recombination in Autographa californica nucleopolyhedrovirus.
Journal of virology - 1 Sept 2002
Crouch Erin A, Passarelli A Lorena
Abstract excerpt
It is known that baculovirus infection promotes high-frequency recombination between its genomes and plasmid DNA during the construction of recombinant viruses for foreign gene expression. However, little is known about the viral genes necessary to promote homologous recombination (HR). We developed an assay to identify viral genes that are necessary to stimulate HR. In this assay, we used two plasmids containing...
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