Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence

27 Jun 2023

Abstract excerpt

ABSTRACT Identification of the mechanisms of viral evasion from human antibodies is crucial both for understanding viral pathogenesis and for designing effective vaccines. Here we show in cell cultures that an N-glycan shield on the herpes simplex virus 1 (HSV-1) envelope glycoprotein B (gB) mediated evasion from neutralization and antibody-dependent cellular cytotoxicity due to pooled γ-globulins derived from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37366623
DOI: 10.1128/mbio.00992-23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulencePMID 37366623Read ↗

Antibody evasion by the N terminus of murid herpesvirus-4 glycoprotein B.Semantic proximity Read ↗

Immunization with Herpes Simplex Virus Nanoparticles Targeting Both Attachment and Fusion Protect Against InfectionSemantic proximity Read ↗

Immune evasion by herpes simplex virus type 1, strategies for virus survival.Semantic proximity Read ↗

Herpes Simplex Virus Evasion of Early Host Antiviral ResponsesSemantic proximity Read ↗

Virion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick GetawaySemantic proximity Read ↗

Broadly Neutralizing Antibodies against HIV-1 As a Novel Aspect of the Immune ResponseSemantic proximity Read ↗

Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.Semantic proximity Read ↗

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent NeutralizationSemantic proximity Read ↗

A cross-neutralizing antibody between HIV-1 and influenza virusSemantic proximity Read ↗

Host Synthesized Carbohydrate Antigens on Viral Glycoproteins as “Achilles’ Heel” of Viruses Contributing to Anti-Viral Immune ProtectionSemantic proximity Read ↗

Herpes simplex virus type 1 evades the effects of antibody and complement in vivo.Semantic proximity Read ↗

Evolving roles of glycosylation in the tug-of-war between virus and hostSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.